Sulfisomidine
Chemical compound
- J01EB01 (WHO)
- 4-amino-N-(2,6-dimethylpyrimidin-4-yl)
benzenesulfonamide
- 515-64-0 N
- 5343
- 5150 Y
- W03L3ODK6E
- D01526 Y
- CHEBI:32166 Y
- ChEMBL485696 Y
- DTXSID1046390
- Interactive image
- O=S(=O)(Nc1nc(nc(c1)C)C)c2ccc(N)cc2
InChI
- InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) Y
- Key:YZMCKZRAOLZXAZ-UHFFFAOYSA-N Y
Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003),[1] sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.
References
- ^ "Changing substance names from BANs to rINNs" (PDF). Archived from the original on 2005-08-27.
{{cite web}}
: CS1 maint: bot: original URL status unknown (link) (34.5 KiB). United Kingdom Medicines and Healthcare products Regulatory Agency (December 12, 2003). Retrieved on 2007-08-26 through Archive.org.
External links
- Melander A, Bitzén PO, Olsson S (1982). "Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections". Acta Medica Scandinavica. 211 (5): 361–4. doi:10.1111/j.0954-6820.1982.tb01962.x. PMID 7051761.
- v
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(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor | |||||||||
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Sulfonamides (DHPS inhibitor) |
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Combinations |
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Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
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Fluoroquinolones |
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Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives |
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Rifamycins/ RNA polymerase | |
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Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it. |
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