Sulfamoxole
Chemical compound
- J01EC03 (WHO)
- 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide
- 729-99-7
- 12894
- DB08798 Y
- 12361 Y
- HGG82XE020
- D02516 Y
- CHEBI:55548 Y
- DTXSID5023617
- Interactive image
- O=S(=O)(Nc1nc(c(o1)C)C)c2ccc(N)cc2
InChI
- InChI=1S/C11H13N3O3S/c1-7-8(2)17-11(13-7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6H,12H2,1-2H3,(H,13,14) Y
- Key:CYFLXLSBHQBMFT-UHFFFAOYSA-N Y
Sulfamoxole is a sulfonamide antibacterial.[1]
References
- ^ Dugger JA (1961). "Sulfamoxole (Nuprin), a new sulfonamide, in pediatric practice". The Journal of New Drugs. 1 (5): 223–9. doi:10.1177/009127006100100506. PMID 13888264.
- v
- t
- e
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor | |||||||||
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Sulfonamides (DHPS inhibitor) |
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Combinations |
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Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
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Fluoroquinolones |
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Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives |
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Rifamycins/ RNA polymerase | |
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Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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- v
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- e