Sulfametrole
Chemical compound
- J01EE03 (WHO) (with trimethoprim)
- In general: ℞ (Prescription only)
- 4-amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)benzenesulfonamide
- 32909-92-5
- 64939
- 58466
- F5AK41IPQG
- D08541 Y
- CHEBI:88258 Y
- DTXSID40865655
- Interactive image
- COc1c(nsn1)NS(=O)(=O)c2ccc(cc2)N
InChI
- InChI=1S/C9H10N4O3S2/c1-16-9-8(11-17-12-9)13-18(14,15)7-4-2-6(10)3-5-7/h2-5H,10H2,1H3,(H,11,13)
- Key:IZOYMGQQVNAMHS-UHFFFAOYSA-N
Sulfametrole (INN) is a sulfonamide antibacterial.
It can be given with trimethoprim.[1]
References
- ^ Plummer FA, Nsanze H, D'Costa LJ, et al. (July 1983). "Single-dose therapy of chancroid with trimethoprim-sulfametrole". N. Engl. J. Med. 309 (2): 67–71. doi:10.1056/NEJM198307143090202. PMID 6343878.
- v
- t
- e
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor | |||||||||
---|---|---|---|---|---|---|---|---|---|
Sulfonamides (DHPS inhibitor) |
| ||||||||
Combinations |
| ||||||||
Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
---|---|---|---|---|---|---|---|---|---|
Fluoroquinolones |
| ||||||||
Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives |
---|
Rifamycins/ RNA polymerase | |
---|---|
Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e