Sulfathiourea
Chemical compound
- J01EB08 (WHO)
- 4-amino-N-(aminocarbonothioyl)benzenesulfonamide
- 515-49-1
- 3000579
- 2272143 Y
- MXF9G4I1V5
- D07239 Y
- CHEBI:131723
- DTXSID4046868
- Interactive image
- O=S(=O)(c1ccc(N)cc1)NC(=S)N
InChI
- InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13) Y
- Key:UEMLYRZWLVXWRU-UHFFFAOYSA-N Y
Sulfathiourea is a sulfonamide antibacterial.[1]
References
- ^ Schoog M (November 1953). "[Sulfathiourea, chemistry, pharmacology and clinical aspects]". Zeitschrift für Haut- und Geschlechtskrankheiten (in German). 15 (10): 315–8. PMID 13137202.
- v
- t
- e
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor | |||||||||
---|---|---|---|---|---|---|---|---|---|
Sulfonamides (DHPS inhibitor) |
| ||||||||
Combinations |
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Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
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Fluoroquinolones |
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Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives |
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Rifamycins/ RNA polymerase | |
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Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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- v
- t
- e